Publications

2018

Transcriptional and epigenetic mechanisms underlying astrocyte identity.

2018, 20181229. Progress in Neurobiology. [Epub ahead of print].

Pavlou MAS, Grandbarbe L, Buckley NJ, Niclou SP, Michelucci A.

https://www.ncbi.nlm.nih.gov/pubmed/30599178

Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks.

2018, 20181227. Nucleic Acids Research. [Epub ahead of print].

Sharma AB, Dimitrov S, Hamiche A, Van Dyck E.

https://www.ncbi.nlm.nih.gov/pubmed/30590707

Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.

2018, 20181207. F1000 Research. 7: 1906. Accepted.

Azuaje F, Kaoma T, Jeanty C, Nazarov P, Muller A, Kim S, Dittmar G, Golebiewska A, Niclou S.

https://f1000research.com/articles/7-1906

Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.

2018, 20181203. Brain Pathology. [Epub ahead of print].

Zeiner PS, Preusse C, Golebiewska A, Zinke J, Iriondo A, Muller A, Kaoma T, Filipski K, Muller-Eschner M, Bernatz S, Blank AE, Baumgarten P, Ilina E, Grote A, Hansmann ML, Verhoff MA, Franz K, Feuerhake F, Steinbach JP, Wischhusen J, Stenzel W, Niclou SP, Harter PN, Mittelbronn M.

https://www.ncbi.nlm.nih.gov/pubmed/30506802

Irradiation to improve the response to immunotherapeutic agents in glioblastomas.

2018, 20181120. Advances in Radiation Oncology. [Epub ahead of print].

Nesseler JP, Schaue D, McBride WH, Lee M-H, Kaprealian T, Niclou SP, Nickers P.

http://www.sciencedirect.com/science/article/pii/S2452109418302380

Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.

2018, 20181101. EMBO reports. 19(11). Epub 2018 Sep 11.

Sousa C, Golebiewska A, Poovathingal SK, Kaoma T, Pires-Afonso Y, Martina S, Coowar D, Azuaje F, Skupin A, Balling R, Biber K, Niclou SP, Michelucci A.

https://www.ncbi.nlm.nih.gov/pubmed/30206190

Revival of the VEGF ligand family?

2018, 20181009. Neuro-Oncology. 20(11): 1421-1422.

Niclou SP.

https://www.ncbi.nlm.nih.gov/pubmed/30137575

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.

2018, 20181005. International Journal of Cancer. [Epub ahead of print].

Johannessen TC, Hasan-Olive MM, Zhu H, Denisova O, Grudic A, Latif MA, Saed H, Varughese JK, Rosland GV, Yang N, Sundstrom T, Nordal A, Tronstad KJ, Wang J, Lund-Johansen M, Simonsen A, Janji B, Westermarck J, Bjerkvig R, Prestegarden L.

https://www.ncbi.nlm.nih.gov/pubmed/30289977

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma.

2018, 20181001. Journal of Cerebral Blood Flow and Metabolism. 38(10): 1741-1753. Epub 2017 Jun 19.

Obad N, Espedal H, Jirik R, Sakariassen PO, Brekke Rygh C, Lund-Johansen M, Taxt T, Niclou SP, Bjerkvig R, Keunen O.

https://www.ncbi.nlm.nih.gov/pubmed/28627960

Actin cytoskeleton remodeling drives breast cancer cell escape from natural killer-mediated cytotoxicity.

2018, 20181001. Cancer Research. 78(19): 5631-5643. Epub 2018 Aug 13.

Al Absi A, Wurzer H, Guerin C, Hoffmann C, Moreau F, Mao X, Brown-Clay J, Petrolli R, Casellas CP, Dieterle M, Thiery JP, Chouaib S, Berchem G, Janji B, Thomas C.

https://www.ncbi.nlm.nih.gov/pubmed/30104240

Microglia in health and disease: A unique immune cell population.

2018, 20180901. Michelucci A, Mittelbronn M and Gomez-Nicola D, eds. Lausanne: Frontiers Media, 2018. 106 p.(Frontiers Research topic).

Michelucci A, Mittelbronn M, Gomez-Nicola D, et al.

https://www.frontiersin.org/research-topics/6533/microglia-in-health-and-disease-a-unique-immune-cell-population

EGFL7 enhances surface expression of integrin alpha5beta1 to promote angiogenesis in malignant brain tumors.

2018, 20180901. EMBO Molecular Medicine. 10(9).

Dudvarski Stankovic N, Bicker F, Keller S, Jones DT, Harter PN, Kienzle A, Gillmann C, Arnold P, Golebiewska A, Keunen O, Giese A, von Deimling A, Bauerle T, Niclou SP, Mittelbronn M, Ye W, Pfister SM, Schmidt MH.

https://www.ncbi.nlm.nih.gov/pubmed/30065025

Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.

2018, 20180719. Autophagy. 14(11): 2007-2022. Epub 2018 Aug 17.

Wang J, Qi Q, Zhou W, Feng Z, Huang B, Chen A, Zhang D, Li W, Zhang Q, Jiang Z, Bjerkvig R, Prestegarden L, Thorsen F, Wang X, Li X, Wang J.

https://www.ncbi.nlm.nih.gov/pubmed/30025493

Investigation of IDH-mutant Gliomas Metabolism by Mass Spectrometry Imaging (Application Note #MSI-16).

2018, 20180625. Imabiotech. 4 p.

Hochart G, Fack F, Tardito S, Stauber J, Fontaine E, Niclou S, Stauber J.

https://www.imabiotech.com/investigation-of-idh-mutant-gliomas-metabolism-by-mass-spectrometry-imaging/

Glioma through the looking GLASS: Molecular evolution of diffuse gliomas and the Glioma Longitudinal AnalySiS Consortium.

2018, 20180618. Neuro-oncology. 20(7): 873-884.

Aldape K, Amin SB, Ashley DM, Barnholtz-Sloan JS, Bates AJ, Beroukhim R, Bock C, Brat DJ, Claus EB, Costello JF, de Groot JF, Finocchiaro G, French PJ, Gan HK, Griffith B, Herold-Mende CC, Horbinski C, Iavarone A, Kalkanis SN, Karabatsou K, Kim H, Kouwenhoven MCM, McDonald KL, Miletic H, Nam DH, Ng HK, Niclou SP, Noushmehr H, Ormond R, Poisson LM, Reifenberger G, Roncaroli F, Sa JK, Sillevis Smitt PAE, Smits M, Souza CF, Tabatabai G, Van Meir EG, Verhaak RGW, Watts C, Wesseling P, Woehrer A, Yung WKA, Jungk C, Hau AC, van Dyck E, Westerman BA, Yin J, Abiola O, Zeps N, Grimmond S, Buckland M, Khasraw M, Sulman EP, Muscat AM, Stead L, Glass Consortium.

https://www.ncbi.nlm.nih.gov/pubmed/29432615

EGFR heterogeneity and implications for therapeutic intervention in glioblastoma.

2018, 20180518. Neuro-Oncology. 20(6): 743-752.

Eskilsson E, Rosland GV, Solecki G, Wang Q, Harter PN, Graziani G, Verhaak RGW, Winkler F, Bjerkvig R, Miletic H.

https://www.ncbi.nlm.nih.gov/pubmed/29040782

Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma.

2018, 20180508. Oncotarget. 9(35): 24041-24053.

Mader L, Blank AE, Capper D, Jansong J, Baumgarten P, Wirsik NM, Zachskorn C, Ehlers J, Seifert M, Klink B, Liebner S, Niclou S, Naumann U, Harter PN, Mittelbronn M.

https://www.ncbi.nlm.nih.gov/pubmed/29844871

Increased formate overflow is a hallmark of oxidative cancer.

2018, 20180410. Nature Communications. 9(1): 1368.

Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton JP, Dornier E, Sumpton D, Mackay GM, Blyth K, Patel KJ, Niclou SP, Vazquez A.

https://www.ncbi.nlm.nih.gov/pubmed/29636461

Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors.

2018, 20180410. Stem Cell Reports. 10(4): 1184-1192.

Kolb J, Anders-Maurer M, Muller T, Hau AC, Grebbin BM, Kallenborn-Gerhardt W, Behrends C, Schulte D.

https://www.ncbi.nlm.nih.gov/pubmed/29641989

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

2018, 20180405. Blood. 131(14): 1617-1621. Epub 2018 Feb 13.

Wierz M, Pierson S, Guyonnet L, Viry E, Lequeux A, Oudin A, Niclou SP, Ollert M, Berchem G, Janji B, Guerin C, Paggetti J, Moussay E.

https://www.ncbi.nlm.nih.gov/pubmed/29439955

DNA methylation-based classification of central nervous system tumours.

2018, 20180322. Nature. 555(7697): 469-474. Epub 2018 Mar 14.

Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Holsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Bruck W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hanggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Muhleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Muller HL, Rutkowski S, von Hoff K, Fruhwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blumcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schuller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM.

https://www.ncbi.nlm.nih.gov/pubmed/29539639

Integrative computational network analysis reveals site-specific mediators of inflammation in Alzheimer's disease.

2018, 20180302. Frontiers in Physiology. 9: 154.

Ravichandran S, Michelucci A, Del Sol A.

https://www.ncbi.nlm.nih.gov/pubmed/29551980