Publications

2016

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

2016, 20161201. Neuro-Oncology. 18(12): 1644-1655. Epub 2016 Jun 10.

Eskilsson E, Rosland GV, Talasila KM, Knappskog S, Keunen O, Sottoriva A, Foerster S, Solecki G, Taxt T, Jirik R, Fritah S, Harter PN, Valk K, Al Hossain J, Joseph JV, Jahedi R, Saed HS, Piccirillo SG, Spiteri I, Leiss L, Euskirchen P, Graziani G, Daubon T, Lund-Johansen M, Enger PO, Winkler F, Ritter CA, Niclou SP, Watts C, Bjerkvig R, Miletic H.

https://www.ncbi.nlm.nih.gov/pubmed/27286795

Combined VEGFR and CTLA-4 blockade increases the antigen-presenting function of intratumoral DCs and reduces the suppressive capacity of intratumoral MDSCs.

2016, 20161101. American Journal of Cancer Research. 6(11): 2514-2531.

Du Four S, Maenhout SK, Niclou SP, Thielemans K, Neyns B, Aerts JL.

https://www.ncbi.nlm.nih.gov/pubmed/27904768

Rapid conversion of mutant IDH1 from driver to passenger in a model of human gliomagenesis.

2016, 20161001. Molecular Cancer Research. 14(10): 976-983. Epub 2016 Jul 18.

Johannessen TA, Mukherjee J, Viswanath P, Ohba S, Ronen SM, Bjerkvig R, Pieper RO.

https://www.ncbi.nlm.nih.gov/pubmed/27430238

Inflammation promotes a conversion of astrocytes into neural progenitor cells via NF-kappaB activation.

2016, 20161001. Molecular Neurobiology. 53(8): 5041-55. Epub 2015 Sep 17.

Gabel S, Koncina E, Dorban G, Heurtaux T, Birck C, Glaab E, Michelucci A, Heuschling P, Grandbarbe L.

https://www.ncbi.nlm.nih.gov/pubmed/26381429

Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells.

2016, 20160901. The Journal of Gene Medicine. 18(9): 234-43.

Hossain JA, Ystaas LR, Mrdalj J, Valk K, Riecken K, Fehse B, Bjerkvig R, Gronli J, Miletic H.

https://www.ncbi.nlm.nih.gov/pubmed/27490042

Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels.

2016, 20160701. The Journal of Biological Chemistry. 291(27): 14274-84. Epub 2016 May 9.

Cordes T, Wallace M, Michelucci A, Divakaruni AS, Sapcariu SC, Sousa C, Koseki H, Cabrales P, Murphy AN, Hiller K, Metallo CM.

https://www.ncbi.nlm.nih.gov/pubmed/27189937

DNA repair mechanisms and their clinical impact in glioblastoma.

2016, 20160621. Mutation Research/Reviews in Mutation Research. 769: 19-35. Epub 2016 Jun 21.

Erasimus H, Gobin M, Niclou S, Van Dyck E.

https://www.ncbi.nlm.nih.gov/pubmed/27543314

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

2016, 20160531. Scientific Reports. 6: 26822.

Rodius S, Androsova G, Gotz L, Liechti R, Crespo I, Merz S, Nazarov PV, de Klein N, Jeanty C, Gonzalez-Rosa JM, Muller A, Bernardin F, Niclou SP, Vallar L, Mercader N, Ibberson M, Xenarios I, Azuaje F.

https://www.ncbi.nlm.nih.gov/pubmed/27241320

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

2016, 20160531. Oncotarget. 7(22): 31955-71.

Bougnaud S, Golebiewska A, Oudin A, Keunen O, Harter PN, Mader L, Azuaje F, Fritah S, Stieber D, Kaoma T, Vallar L, Brons NH, Daubon T, Miletic H, Sundstrom T, Herold-Mende C, Mittelbronn M, Bjerkvig R, Niclou SP.

https://www.ncbi.nlm.nih.gov/pubmed/27049916

Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.

2016, 20160501. Neurobiology of disease. 89: 112-25. Epub 2016 Feb 1.

Meiser J, Delcambre S, Wegner A, Jager C, Ghelfi J, d'Herouel AF, Dong X, Weindl D, Stautner C, Nonnenmacher Y, Michelucci A, Popp O, Giesert F, Schildknecht S, Kramer L, Schneider JG, Woitalla D, Wurst W, Skupin A, Weisenhorn DM, Kruger R, Leist M, Hiller K.

https://www.ncbi.nlm.nih.gov/pubmed/26836693

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis.

2016, 20160322. Oncotarget. 7(12): 13688-705.

Hoffmann C, Mao X, Dieterle M, Moreau F, Al Absi A, Steinmetz A, Oudin A, Berchem G, Janji B, Thomas C.

https://www.ncbi.nlm.nih.gov/pubmed/26883198

Practical considerations for omics experiments in biomedical sciences.

2016, 20160317. Current Pharmaceutical Biotechnology. 17(1): 105-114.

Vaudel M, Barsnes H, Bjerkvig R, Bikfalvi A, Selheim F, Berven FS, Daubon T.

https://www.ncbi.nlm.nih.gov/pubmed/26278526

Experimental therapies: gene therapies and oncolytic viruses.

2016, 20160308. Handbook of Clinical Neurology. 134: 183-97.

Hulou MM, Cho CF, Chiocca EA, Bjerkvig R.

https://www.ncbi.nlm.nih.gov/pubmed/26948355

Transcriptomic analyses of primary astrocytes under TNF α treatment.

2016, 20160301. Genomics Data. 7: 7-11.

Birck C, Koncina E, Heurtaux T, Glaab E, Michelucci A, Heuschling P, Grandbarbe L.

https://www.ncbi.nlm.nih.gov/pubmed/26981349

Gene regulatory network inference of Immunoresponsive Gene 1 (IRG1) identifies Interferon Regulatory Factor 1 (IRF1) as its transcriptional regulator in mammalian macrophages.

2016, 20160212. PLoS One. 11(2): e0149050.

Tallam A, Perumal TM, Antony PM, Jager C, Fritz JV, Vallar L, Balling R, Del Sol A, Michelucci A.

https://www.ncbi.nlm.nih.gov/pubmed/26872335

Targeted proteomics to assess the response to anti-angiogenic treatment in human glioblastoma (GBM).

2016, 20160201. Molecular & Cellular Proteomics. 15(2): 481-92. Epub 2015 Aug 4.

Demeure K, Fack F, Duriez E, Tiemann K, Bernard A, Golebiewska A, Bougnaud S, Bjerkvig R, Domon B, Niclou SP.

https://www.ncbi.nlm.nih.gov/pubmed/26243272

Maximizing the efficacy of MAPK-targeted treatment in PTENLOF/BRAFMUT melanoma through PI3K and IGF1R inhibition.

2016, 20160115. Cancer Research. 76(2): 390-402. Epub 2015 Nov 17.

Herkert B, Kauffmann A, Molle S, Schnell C, Ferrat T, Voshol H, Juengert J, Erasimus H, Marszalek G, Kazic-Legueux M, Billy E, Ruddy D, Stump M, Guthy D, Ristov M, Calkins K, Maira SM, Sellers WR, Hofmann F, Hall MN, Brachmann SM.

https://www.ncbi.nlm.nih.gov/pubmed/26577700

Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells.

2016, 20160105. Oncotarget. 7(1): 593-609. Epub 2015 nov 11.

Podergajs N, Motaln H, Rajcevic U, Verbovsek U, Korsic M, Obad N, Espedal H, Vittori M, Herold-Mende C, Miletic H, Bjerkvig R, Turnsek TL.

https://www.ncbi.nlm.nih.gov/pubmed/26573230